Nanoscale infrared microscopy enables label-free, chemical imaging, and spectroscopy at the nanometre scale by combining atomic force microscopy (AFM) with infrared radiation. Photothermal AFM-IR allows the simultaneous analysis of the chemical, mechanical, and structural properties of materials and heterogeneous biological matter, such as single-molecules and individual monolayers.

Highlights will include:

• Overview of the working principle of Photothermal AFM-IR
• Latest technical advances
• Outline of modes suitable for biological samples, their advantages and limitations
• Innovative applications in life science research

Dr. Ruggeri will speak about the photothermal AFM-IR technique and using it to determine the molecular fingerprint of biomolecules, the secondary structure of protein and their assemblies, and unravel protein phase transitions in healthy and diseased states.

Dr. Francesco Simone Ruggeri
Assoc. Prof. of Nanoscale Microscopy and Spectroscopy
Wageningen University and Research (WUR), Netherlands

Dr. Cassandra Phillips
Senior Product Manager
Bruker NanoIR

Dr. Qichi Hu
Senior Staff Applications Scientist
Bruker NanoIR